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The common theme of research projects in the Sisk Lab is the influence of gonadal steroid hormones on nervous system structure and function during adolescence. The juvenile-to-adult transition is a fundamental period of neural development that involves many of the same processes that occur during initial construction of the nervous system, such as neurogenesis, cell death, and synapse formation and pruning. Thus, adolescence is a type of metamorphosis during which the nervous system acquires the new functions that characterize adult social behaviors and cognition. Our work is primarily focused on the role that pubertal gonadal hormones play in this metamorphosis. Research in the Sisk Lab is a combination of neuroendocrinology, developmental neurobiology, functional neuroanatomy, and behavioral neuroscience. We employ a variety of experimental techniques, ranging from analysis of gene expression to analysis of behavior.

 

 





Updated February 2013 by Maggie Mohr