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Research News

Spring 2008
 

Staff changes

 

Haywood takes on regulatory affairs

Ask JR Haywood about regulations governing research and he cites balance. The new interim assistant vice president for regulatory affairs promises to work to balance the mission components of the Office of Regulatory Affairs (ORA): comply with rules and regulations governing research, protect research subjects, facilitate research.

Units in the Office of Regulatory Affairs include

  • Human Research Protection Program
  • Animal Care Program
  • Environmental Health and Safety
  • Regulatory Components of the Enterprise Business System

The export controls and trade sanctions program is under the direction of the associate vice president for research and graduate studies.

“JR Haywood brings a wealth of experience and energy to help keep MSU compliant,” says VP Gray. “We’re fortunate that he’s willing to step into this interim position.”

“ORA has a great staff,” Haywood says. Judy McMillan, a certified institutional review board (IRB) professional who has been administrator of the Biomedical and Health Institutional Review Board, recently was named director of the human research protection program (HRPP). Peter Vasilenko remains chair of the IRBs. “Peter has worked tirelessly toward effectiveness and national recognition of MSU’s HRPP,” Haywood says. “I appreciate his efforts over the years as HRPP director.” In other staff changes, Kristen Burt, who has been the education coordinator for ORA, was named assistant to the assistant vice president for regulatory affairs. Renee Bockes joined ORA from the College of Business as a resource administrator. “These dedicated staff members have been working hard to keep MSU compliant, and I know I can count on them.” Haywood says.

It’s absolutely essential to remain compliant, he adds. “Even doing more than is required, as the accrediting agencies for research subjects expect, is a good thing.” But, he cautions, regulatory procedures can stifle research if they aren’t handled carefully. Haywood believes in “administration for research,” rather than administration of research, and will focus on compliance while working to avoid a heavy regulatory burden for researchers.

That kind of balance isn’t always easy to accomplish, he concedes. “It’s been part of a national discussion for at least a decade,” he says, citing a 1998 National Institutes of Health report that said the heaviest regulatory burden occurs in institutions, not at the agency level.

Haywood, who has been assistant vice president for animal care programs, has a long-standing interest in research regulations, with more than twenty years of involvement with animal care issues at both institutional and national levels. That interest grew out of his own research. A professor of pharmacology and toxicology and chair of the department, he studies the role of the brain in high blood pressure, specifically the impact of changes in brain chemicals. At least 40 chemicals are present in any brain synapse, he says. Just about anything can change the signals they release. He models sodium- and obesity-induced hypertension to see what role those factors play in elevating blood pressure.

Haywood will continue as chair of the Department of Pharmacology and Toxicology with extra help from associate chair James Galligan. “This is a great department,” Haywood says. “I can’t say enough good things about the faculty.”

The department launched a new online professional master’s degree last fall. “So far, with news about it traveling mostly by word of mouth, we’ve had something like 200 inquiries already,” Haywood says. The program was designated a Professional Science Masters in Integrative Pharmacology by the Council of Graduate Schools and enrolled its first ten students this spring. “They’re from all over the country,” he notes. “We hope to be able to include international students, too.”

The entire program is offered online, two courses each semester with only a one-week on-campus residency required. The program aims to provide opportunities for additional training that can lead to advancement for technicians and entry level scientists in pharmaceutical and other industries. An advisory board with industry representatives helps guide the program.

The department has also established the In Vivo Pharmacology Center to offer high quality standard and specialized assays, education, and investigative and drug development services to customers. The opportunity to hire scientists formerly employed in drug safety research and development at Parke-Davis/Pfizer made this new facility possible, Haywood says. Marc Bailie, who spent eleven years developing and directing the Safety Pharmacology Group at Parke-Davis/Pfizer, directs the new center. Teresa Krieger-Burke, with expertise in general and reproductive toxicology and safety pharmacology, is associate director. Sarah Marsh, a veterinary technologist with experience at the MSU Veterinary Hospital as well as Parke-Davis/Pfizer, is laboratory manager.

Linda Triemer takes Chicago position

After more than five years working on regulatory matters at MSU, Linda Triemer left in April to become director of research integrity at the University of Chicago. There she works with the associate vice president for research administration to oversee their human protection program, financial conflicts of interest, and other regulatory areas.

At MSU Triemer worked with four assistant vice presidents and the transition from the Office of Research Ethics and Standards to the Office of Regulatory Affairs. Although her efforts touched all the regulatory areas, her primary focus was on programs protecting human subjects of research.

Triemer led MSU through the process of achieving accreditation from the Association for the Accreditation of Human Research Protection Programs (AAHRPP). “We had our first meetings about accreditation in June 2003,” she recalls. MSU received full accreditation in March of 2006 and last month applied for reaccreditation.

Her AAHRPP experience led to her becoming a site visitor for the association, a role she will retain in her new position. The University of Chicago has a teaching hospital and five institutional review boards (IRBs), compared to three IRBs at MSU.

Triemer also led MSU’s response to new patient privacy regulations in the Health Insurance Portability and Accountability Act (HIPAA) as they affected research. She chaired the HIPAA board, including people who were already working on patient privacy issues MSU and integrating that board with the IRBs. “This is a different approach from what most universities did,” she says. “Our goal was to keep the regulatory burden as low as possible for researchers.”

Before coming to MSU, Triemer was director of research and information at PRONJ, a medical peer review organization assessing quality of care for Medicare and Medicaid patients in New Jersey. Previously she was head of the science group for a Manhattan law firm where she advised attorneys on the scientific evidence to be used in arguing their cases and was a faculty member at the University of Medicine and Dentistry of New Jersey. Her research on human exposure to volatile organics led to a position as an environmental scientist at ExxonMobil. Her six years there—she began a month before the Valdez oil spill in Alaska—cemented her understanding of regulatory issues, she says. “Because industrial scientists are often perceived as biased, it was important to address actual conflicts of interest carefully.” 

In addition to her position in the Office of Regulatory Affairs at MSU, Triemer was an adjunct professor of epidemiology. She earned her Ph.D. in public health sciences at the University of Illinois at Chicago.

Despite her move, Triemer isn’t giving up her Spartan spirit. Her husband, Richard Triemer, will remain at MSU as chair of the Department of Plant Biology. “I’ll be back on weekends,” she says, and promises to continue to cheer for MSU athletic teams.

“Linda was very helpful in the leadership transitions in our compliance area and in helping develop the Office of Regulatory Affairs into its current strong position,” says VP Gray. “We were fortunate to have her leading our accreditation efforts. We’ll miss her, but we wish her well in her new position.”