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Gray
 

Investing to build biomedical research

Just days into his new job as Vice President for Research and Graduate Studies in September 2004, Ian Gray and then-Provost Lou Anna Simon charged the Science and Technology Subcommittee (STC) of the University Research Council to develop a plan for increasing funding from the National Institutes of Health (NIH).

The research associate deans began by examining MSU’s current NIH funding. What they found was a very small number of large collaborative program project and center grants compared to the number of individual-investigator grants. Changing that ratio would have a large impact on increasing overall NIH funding, they concluded. The STC settled on a planning strategy to solicit a series of white papers that would identify research teams and resources needed to compete successfully for NIH center grants of $4-$5 million.

That fall, the research associate deans, led by Justin McCormick, College of Osteopathic Medicine, and Estelle McGroarty, College of Natural Science, gathered groups of researchers to begin identifying MSU’s strengths in the health and biomedical sciences. “What we found,” McCormick recalls, “was that some groups already existed and a few of them were quite mature. They included investigators who had been working together for a while, and they had a number of individual NIH grants.” With a little boost, those groups would be ready almost immediately to apply for a center grant.

Other faculty groups discovered each other during the process, forming new collaborations and looking for ways to link their efforts to pursue center grants.

By December 2004 fifteen multidisciplinary groups had coalesced and drafted white papers summarizing their research activities and plans for growth. With feedback from the associate deans, the groups revised their proposals, and last summer the STC reviewed the final white papers and presentations from each of the groups.

The STC made tentative program funding recommendations to VP Gray and the deans using the following criteria:

bulletMaturity – How close is the group to developing a collaborative, multi-investigator NIH proposal?
bulletLeadership – Is there a clear leader who will push the multi-investigator concept forward?
bulletPrior NIH funding – Are there enough NIH R01 or similar grants that the group can realistically submit a multi-investigator proposal?
bulletMentoring – Is there evidence of a plan to help junior faculty develop into independent investigators with NIH support?
bulletStrategies – Is there a clearly developed strategy to ensure continued viability of the investigative team and the topic under investigation?

“The resource requests fell into three categories,” McGroarty reported. The categories were faculty hires, core facilities that would also benefit other research areas, and program enhancement requests. VP Gray accepted the recommendations and funded ten groups (see sidebar).

“I think the exercise we went through meshed well with the process colleges conducted to request quality funds,” says VP Gray. Provost Kim Wilcox recently announced the funding decisions from the Fund for the Enhancement of Academic Quality. “Some of the new faculty positions identified to support academics will also respond to the needs identified in the health and biomedical research white papers,” Gray notes.

Another request for white papers is anticipated this year, Gray says. “We’ll also be watching the progress of the ten groups funded. We’re investing a substantial amount of MSU funds; we’ll be looking for a good return.”

 

 

The OVPRGS invested funds in the following groups to develop proposals for NIH centers:

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Infectious Disease and Immunology; Carole Bolin, Walter Esselman, Terence Marsh, Martha Mulks
 

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Reproductive and Developmental Sciences; Jeanne Burton, Gloria Perez, George Smith
 

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Development of an NCI-Designated Cancer Center, including Steroid Hormone / Growth Factor Cross-Talk in Breast Cancer Progression, Colon Epithelial Cells Exposed to Probiotic Bacteria Modify Macrophage Activation and Chemotaxis in Response to a Bacterial Pathogen, Translational Model of Low Dose Metronomic Antiangiogenic Therapy in Canine Spontaneous Tumors; Raymond Demers, Justin McCormick, Kathleen Gallo, Norman Hord, Barbara Kitchell
 

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Health Disparities and Social Justice; Stephen Esquith
 

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Cardiovascular Research; Gregory Fink
 

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Health Behavior and Social Institutions; John Goddeeris, Steven Haider
 

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Neurobiology, Cognition and Behavior; David Kaufman, Joel Nigg
 

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Environment and Health; Jennifer Olson, David Campbell, Susan Ewart, Tom Dietz
 

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Chronic Respiratory Diseases; Jack Harkema, Norbert Kaminski, N. Edward Robinson
 

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Food and Health Initiative; Gale Strasburg