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Investing to build biomedical
research
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Just days into his new job as Vice
President for Research and Graduate Studies in September 2004, Ian Gray
and then-Provost Lou Anna Simon charged the Science and Technology
Subcommittee (STC) of the University Research Council to develop a plan for
increasing funding from the National Institutes of Health (NIH).
The research associate deans began by
examining MSU’s current NIH funding. What they found was a very small number
of large collaborative program project and center grants compared to the
number of individual-investigator grants. Changing that ratio would have a
large impact on increasing overall NIH funding, they concluded. The STC
settled on a planning strategy to solicit a series of white papers that
would identify research teams and resources needed to compete successfully
for NIH center grants of $4-$5 million.
That fall, the research associate deans,
led by Justin McCormick, College of Osteopathic Medicine, and
Estelle McGroarty, College of Natural Science, gathered groups of
researchers to begin identifying MSU’s strengths in the health and
biomedical sciences. “What we found,” McCormick recalls, “was that some
groups already existed and a few of them were quite mature. They included
investigators who had been working together for a while, and they had a
number of individual NIH grants.” With a little boost, those groups would be
ready almost immediately to apply for a center grant.
Other faculty groups discovered each
other during the process, forming new collaborations and looking for ways to
link their efforts to pursue center grants.
By December 2004 fifteen
multidisciplinary groups had coalesced and drafted white papers summarizing
their research activities and plans for growth. With feedback from the
associate deans, the groups revised their proposals, and last summer the STC
reviewed the final white papers and presentations from each of the groups.
The STC made tentative program funding
recommendations to VP Gray and the deans using the following criteria:
 | Maturity – How close is the group to
developing a collaborative, multi-investigator NIH proposal? |
 | Leadership – Is there a clear leader
who will push the multi-investigator concept forward? |
 | Prior NIH funding – Are there enough
NIH R01 or similar grants that the group can realistically submit a
multi-investigator proposal? |
 | Mentoring – Is there evidence of a
plan to help junior faculty develop into independent investigators with
NIH support? |
 | Strategies – Is there a clearly
developed strategy to ensure continued viability of the investigative team
and the topic under investigation? |
“The
resource requests fell into three categories,” McGroarty reported. The
categories were faculty hires, core facilities that would also benefit other
research areas, and program enhancement requests. VP Gray accepted the
recommendations and funded ten groups (see sidebar).
“I think
the exercise we went through meshed well with the process colleges conducted
to request quality funds,” says VP Gray. Provost Kim Wilcox recently
announced the funding decisions from the
Fund for the Enhancement of Academic Quality. “Some of the new faculty
positions identified to support academics will also respond to the needs
identified in the health and biomedical research white papers,” Gray notes.
Another request for white papers is
anticipated this year, Gray says. “We’ll also be watching the progress of
the ten groups funded. We’re investing a substantial amount of MSU funds;
we’ll be looking for a good return.” |
The OVPRGS invested funds in
the following groups to develop proposals for NIH centers:
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Infectious Disease and Immunology; Carole
Bolin, Walter Esselman, Terence Marsh, Martha Mulks
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Reproductive and Developmental Sciences;
Jeanne Burton, Gloria Perez, George Smith
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Development of an NCI-Designated Cancer
Center, including Steroid Hormone / Growth Factor Cross-Talk in Breast
Cancer Progression, Colon Epithelial Cells Exposed to Probiotic Bacteria
Modify Macrophage Activation and Chemotaxis in Response to a Bacterial
Pathogen, Translational Model of Low Dose Metronomic Antiangiogenic
Therapy in Canine Spontaneous Tumors; Raymond Demers, Justin McCormick,
Kathleen Gallo, Norman Hord, Barbara Kitchell
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Health Disparities and Social Justice;
Stephen Esquith
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Cardiovascular Research;
Gregory Fink
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Health Behavior and Social Institutions;
John Goddeeris, Steven Haider
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Neurobiology, Cognition and Behavior; David
Kaufman, Joel Nigg
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Environment and Health; Jennifer Olson,
David Campbell, Susan Ewart, Tom Dietz
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Chronic Respiratory Diseases;
Jack Harkema, Norbert Kaminski, N. Edward Robinson
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Food and Health Initiative; Gale Strasburg
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